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10-4931

Velpatasvir

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£139.00

SKU:
10-4931
Additional Names:
GS-5816
Physical State:
Solid
Molecular Weight:
883.02
Purity:
98%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
1377049-84-7
Immunogen:
Protease
Extra Details:
Velpatasvir is an extremely potent pan-genotypic hepatitis C virus (HCV) NS5A inhibitor.1 It is a component of Epclusa® and Vosevi®, two clinically useful medications with 98% and 97%, respectively, cure rates for HCV. It displayed EC50's for GTs 1-4, 6a ranging from 6-16 pM, GT5a at 75 pM, and GT6e at 130 pM. Velpatasvir also displayed an excellent barrier to viral resistance. It has been shown in silico, that velpatasvir binds to the SARS-CoV-2 spike protein and may be a potential therapeutic.2
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Ambient