10-4919
TJ-M2010-5
Size
£168.00
- SKU:
- 10-4919
- Physical State:
- Solid
- Molecular Weight:
- 406.55
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1357471-57-8
- Immunogen:
- TLR (Toll-like receptor)
- Extra Details:
- TJ-M2010-5 is an inhibitor of the toll-like receptor(TLR)/adaptor molecule myeloid differentiation factor 88 (MyD88) signaling pathway, crucial for inflammation and associated with the development of many inflammation-related cancers.1 It ameliorates ischemia-reperfusion injury in various organ models including brain2, liver3, and heart4. TJ-M2010-5 also suppressed proliferation, migration, and invasion in MCF-7 and MDA-MB-231 breast cancer cells.5 It prevented colitis-associated colorectal cancer by impairing myeloid-derived suppressor cells.6
- Shipping Conditions:
- Ambient