DC-Y13-27

Size

£149.00

SKU:: 10-4884
Additional Names:: (E)-2-Cyano-3-[5-(3-hydroxyphenyl)thiophen-2-yl]acrylamide
Physical State:: Solid
Molecular Weight:: 270.31
Purity:: >98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 3069691-93-6
Immunogen:: RNA
Extra Details:: DC-Y13-27 is an inhibitor (IC50 = 21.8 uM) of the RNA N6-methyladenosine (m6A) reader YTHDF2.1 It significantly enhanced tumor growth inhibition in MC38 murine models in conjunction with radiotherapy and/or anti-PD-L1 therapy via an increase in the number of CD8+ T cells.