10-4861
GSK872
Size
£158.00
- SKU:
- 10-4861
- Additional Names:
- GSK'872|GSK2399872A
- Physical State:
- Solid
- Molecular Weight:
- 383.49
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1346546-69-7
- Immunogen:
- Inflammasome|Kinase
- Extra Details:
- GSK872 is a potent (IC50 = 1.8nM domain binding; IC50 = 1.3 nM kinase activity) and selective inhibitor of receptor interacting protein 3 (RIP3).1 It is able to prevent necroptosis, virus-induced necrosis, and TLR3-induced necrosis.1,2 GSK872 can induce Caspase8-mediated apoptosis at higher concentrations (e.g.3 uM).2
- Shipping Conditions:
- Ambient