10-4860
Necrosulfonamide
Size
£144.00
- SKU:
- 10-4860
- Physical State:
- Solid
- Molecular Weight:
- 461.47
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1360614-48-7
- Immunogen:
- Kinase
- Extra Details:
- Specifically blocks necroptosis downstream of RIP3 activation by preventing MLKL-RIP3 interaction.1 Displays neuroprotective effects after ischemic brain injury.2 Prevents cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells.3 Binds to gasdermin D inhibiting pyroptosis and associated inflammatory cell death and sepsis.4 Rescues cells from TLR3 ligand-induced death.5
- Shipping Conditions:
- Ambient