10-4849
UZH2
Size
£216.00
- SKU:
- 10-4849
- Physical State:
- Solid
- Molecular Weight:
- 513.64
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 2756566-45-5
- Immunogen:
- Methyltransferase|Nucleic acid methylation|RNA
- Extra Details:
- UZH2 (2756566-45-5) is a potent (IC50 = 5 nM) and selective (against METTL1 and METTL16) inhibitor of the RNA methyltransferase METTL3, a key component of the writer complex targeting N6-methyladenosine (m6A), the most common RNA modification. It was able to impair cell growth (GI50 = 12 uM) in MOLM-13 cancer cells (AML).
- Shipping Conditions:
- Ambient