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10-4817

NVP-BGJ398

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£163.00

SKU:
10-4817
Additional Names:
Infigratinib
Physical State:
Solid
Molecular Weight:
560.48
Purity:
99%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
872511-34-7
Immunogen:
Kinase
Extra Details:
NVP-BGJ398 is a potent and selective pan-FGFR inhibitor (IC50 = 0.9nM, 1.4 nM, 1.0 nM, and 60 nM for FGFR1,2,3,4 respectively).1 It has also been used in a mouse model of Achondroplasia (most common form of dwarfism) to correct pathological hallmarks of this condition.2
Shipping Conditions:
Ambient