10-4813
Quizartinib
Size
£149.00
- SKU:
- 10-4813
- Additional Names:
- AC220
- Physical State:
- Solid
- Molecular Weight:
- 560.67
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 950769-58-1
- Immunogen:
- Cytochrome/MDR|Kinase
- Extra Details:
- Quizartinib is a potent and selective inhibitor of FLT3 (Kd = 1.6nM, IC50 = 0.56 nM MV4-11 cells).1 It is in clinical trials for treatment of Acute Myelogenous Leukemia (AML).2,3 Quizartinib priming resulted in prevention of myelosuppression in mice treated with 5-FU and Gemcitabine.4 Quizartinib showed significant reversal of ABCG2-mediated multidrug resistance (@ 3 uM) via antagonism of drug efflux function.5,6
- Shipping Conditions:
- Ambient