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10-4789

Binimetinib

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£144.00

SKU:
10-4789
Additional Names:
ARRY-162|MEK162
Physical State:
Solid
Molecular Weight:
441.23
Purity:
99%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
606143-89-9
Immunogen:
Kinase
Extra Details:
Binimetinib (606143-89-9) is a potent (IC50 = 12 nM) and selective allosteric inhibitor of MEK1/2.1,2 Recently approved by the FDA for treatment of melanoma in combination with Encorafenib. Binimetinib has had limited success as monotherapy but has shown promise in combination with other chemotherapeutic agents.3-5
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Ambient