10-4784
Fruquintinib
Size
£158.00
- SKU:
- 10-4784
- Additional Names:
- HMPL-013
- Physical State:
- Solid
- Molecular Weight:
- 393.40
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1194506-26-7
- Immunogen:
- Kinase
- Extra Details:
- Fruquintinib is a potent and highly selective inhibitor of VEGFR kinase (IC50's: VEGFR1= 33 nM, VEGFR2 = 35 nM, VEGFR3 = 0.5 nM).1 It potently inhibited VEGF/VEGFR signaling and cell proliferation in HUVECs and HLECs and prevented angiogenesis in vitro. Fruquintinib is currently is several clinical trials against metastatic colorectal cancer2 and nonsquamous non-small-cell lung cancer3.
- Shipping Conditions:
- Ambient