10-4780
JNK-IN-8
Size
£149.00
- SKU:
- 10-4780
- Additional Names:
- JNK Inhibitor XVI
- Physical State:
- Solid
- Molecular Weight:
- 507.6
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1410880-22-6
- Immunogen:
- Kinase
- Extra Details:
- JNK-IN-8 is a potent and selective irreversible JNK inhibitor (IC50s=4.67, 18.7 and 0.98 nM for JNK1, 2 and 3 respectively).1 JNK blockade with JNK-IN-8 overcomes PD-L1-mediated resistance to chemotherapy in colorectal cancer.2 Improves ARDS-induced cognitive impairment by inhibition of JNK/NF-kB-mediated NLRP3 inflammasome activation.3
- Shipping Conditions:
- Ambient