SNS-314 mesylate

Size

£168.00

SKU:: 10-4779
Physical State:: Solid
Molecular Weight:: 527.04
Purity:: 98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 1146618-41-8
Immunogen:: Kinase
Extra Details:: SNS-314 is a potent and selective pan-Aurora kinase inhibitor (IC50's: Aurora A = 9 nM, Aurora B = 31 nM, Aurora C = 3 nM.1,2 It was able to inhibit proliferation in a wide panel of human cancer cell lines including colon (HCT116), breast (MDA-MB-231), prostate (PC-3), lung (H1299, Calu-6), ovarian (A2780), melanoma (A375) and liver (SMMC-7721, HepG2, LM6).1-4