10-4764
LDN-193189 HCl
Size
£158.00
- SKU:
- 10-4764
- Additional Names:
- DM-3189
- Physical State:
- Solid
- Molecular Weight:
- 479.4
- Purity:
- 99%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1435934-00-1
- ABP:
- No Import Docs
- Immunogen:
- Kinase
- Extra Details:
- LDN-193189 2HCl is a potent and selective inhibitor of ALK2 (IC50 = 5 nM) and ALK3 (IC50 = 30 nM), thereby inhibiting SMAD1/5/8 phosphorylation.1 Only weak inhibition of ALK4, ALK5, and ALK7 is observed. Promotes neuronal differentiation of human pluripotent stem cells.2-3 LDN-193189 HCl has also been used to examine the role of osteogenesis in prostate tumor metastases in bone.4
- Shipping Conditions:
- Ambient