10-4731
(R)-(+)Etomoxir Na
Size
£158.00
- SKU:
- 10-4731
- Physical State:
- Solid
- Molecular Weight:
- 320.74
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 828934-41-4
- Immunogen:
- Acyltransferase
- Extra Details:
- Etomoxir (828934-41-4) is an irreversible inhibitor of mitochondrial carnitine palmitoyl transferase 1 (CPT1).1 It is widely used to study fatty acid oxidation. Etomoxir has been investigated as a therapeutic agent for heart disease2, diabetes3, and cancer4,5. Use of etomoxir in concentrations greater than 5 uM induces acute production of ROS with associated evidence of severe oxidative stress in proliferating T cells indicating a loss of specificity for CTP1 at these concentrations.6 200 uM etomoxir inhibited complex I of the electron transport chain.7
- Shipping Conditions:
- Ambient