10-4717
BT2
Size
£149.00
- SKU:
- 10-4717
- Physical State:
- Solid
- Molecular Weight:
- 247.10
- Purity:
- 95%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 34576-94-8
- Immunogen:
- Kinase
- Extra Details:
- BT2 is an inhibitor of the mitochondrial branched-chain A Alpha-ketoacid dehydrogenase complex kinase (BCKDC) - IC50 = 3.19 uM.1 Inhibition of this kinase has been shown to reduce levels of branched-chain amino acid concentrations in vivo. BT2 has also been shown to be a moderate inhibitor (Ki = 59 uM) of myeloid cell leukemia 1(Mcl 1), a Bcl-2 family protein.2
- Shipping Conditions:
- Ambient