10-4714
KC7F2
Size
£158.00
- SKU:
- 10-4714
- Physical State:
- Solid
- Molecular Weight:
- 570.38
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 927822-86-4
- Immunogen:
- Transcription factor
- Extra Details:
- KC7F2 is an inhibitor of HIF-1A Alpha (IC50 = 20 uM).1 It inhibited HIF-mediated transcription in cells derived from glioma, breast, and prostate cancers. The mechanism of action of KC7F2 is via down-regulation of HIF-1A Alpha protein synthesis accompanied by suppression of phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 and p70 S6 kinase, key regulators of HIF-1A Alpha protein synthesis.
- Shipping Conditions:
- Ambient