Ezatiostat

Size

£163.00

SKU:: 10-4711
Additional Names:: TER199|TLK199
Physical State:: Solid
Molecular Weight:: 529.65
Purity:: 98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 168682-53-9
Immunogen:: Glutathione
Extra Details:: Ezatiostat is a peptidomimetic inhibitor of glutathione S-transferase P1-1 (GSTP1).1,2 It showed significant hematopoietic stimulatory activity possibly via JNK activation through disruption of the GSTP/JNK interaction.3 Ezatiostat displayed efficacy in treating myelodysplastic syndrome.4,5 Combined treatment with ezatiostat and a PRDX6 inhibitor displayed synergistic effects in the treatment of neuroblastoma in vitro and in vivo.6