Glumetinib

Size

£187.00

SKU:: 10-4690
Additional Names:: SCC244
Physical State:: Solid
Molecular Weight:: 459.48
Purity:: 98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 1642581-63-2
Immunogen:: Kinase
Extra Details:: Highly selective (2400-fold selectivity against a panel of 312 kinases) and potent (IC50 = 0.42 nM) inhibitor of c-Met kinase. It induced tumor regression in MET-driven CDX (MKN-45, SNU-5, EBC-1) and PDX (4 NSCLC, 5 HCC) tumor models.