10-4675
AZ20
Size
£153.00
- SKU:
- 10-4675
- Physical State:
- Solid
- Molecular Weight:
- 412.51
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1233339-22-4
- Immunogen:
- Kinase
- Extra Details:
- AZ20 is a potent and highly selective inhibitor of Ataxia telangiectasia mutated and RAD3-related (ATR) kinase (IC50 = 5 nM in vitro; IC50 = 50 nM in HT29 colorectal adenocarcinoma cells).1 Combination therapy with AZ20 and gemcitabine resulted in synergistic inhibition of tumor cell growth and cell death initiation in pancreatic cancer cell lines.2
- Shipping Conditions:
- Ambient