10-4672
Luminespib
Size
£144.00
- SKU:
- 10-4672
- Additional Names:
- NVP-AUY922|VER-52296
- Physical State:
- Solid
- Molecular Weight:
- 465.54
- Purity:
- >99%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 747412-49-3
- Immunogen:
- HSP (Heat shock protein)
- Extra Details:
- Luminespib is a potent inhibitor (IC50 = 21 nM) of HSP90.1 It is active against various human tumor xenograft models acting via several processes including cytostasis, apoptosis, invasion, and angiogenesis.2,3 Luminespib enhances tumor susceptibility to T-cell-based immunotherapy by re-invigorating the cancer-immunity cycle in NANOG+ cancer cells.4 It also acts as a radiosensitizer against various tumor cells.5-7
- Shipping Conditions:
- Ambient