Repaglinide

Size

£139.00

SKU:: 10-4661
Physical State:: Solid
Molecular Weight:: 453.6
Purity:: >98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 135062-02-1
Immunogen:: Ion channel
Extra Details:: Repaglinide is a blocker of the ATP-sensitive potassium channel Kir6 with hypoglycemic activity.1 Clinically useful antidiabetic agent. It displays 30-fold selectivity for pancreatic Kir6.2/SUR1 over cardiac Kir6.1/SUR2B and Kir6/SUR2A channels.2 Repaglinide displayed neuroprotective effects in Huntington disease3, Parkinson's disease4, and ALS5 via blockade of the DREAM-ATF6 interaction.