10-4635
PF-9366
Size
£158.00
- SKU:
- 10-4635
- Physical State:
- Solid
- Molecular Weight:
- 350.85
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 72882-78-1
- Extra Details:
- PF-9366 is an allosteric inhibitor (IC50 = 420 nM) of methionine adenosyltransferase 2A (Mat2A), the primary enzyme responsible for extrahepatic synthesis of S-adenosyl-L-methionine (SAM).1 It inhibited cellular SAM production in H520 lung and Huh-7 liver cancer cells with IC50's of 1.2 uM and 225 nM respectively.
- Shipping Conditions:
- Ambient