CDN1163

Size

£153.00

SKU:: 10-4627
Physical State:: Solid
Molecular Weight:: 320.39
Purity:: 98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 892711-75-0
Immunogen:: ATPase|ER/Golgi|UPR (Unfolded protein response)
Extra Details:: Allosteric activator of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA).1,2 It lowered fasting glucose levels, improved glucose tolerance, and ameliorated hepatitis steatosis in ob/ob mice.1 CDN1163 also rescued neurons from ER-stress-induced cell death in vitro and displayed significant efficacy in a rat 6-hydroxydopamine (6-OHDA) model of Parkinson's disease.2 It reduced age-related muscle atrophy and weakness in a C57BL/6J mice.3 CDN1163 decreased inflammatory cytokines and chemokines and attenuated mitochondrial dysfunction in Influenza A infected H1395 cells.4