10-4546
RepSox
Size
£163.00
- SKU:
- 10-4546
- Additional Names:
- 616452|E-616452|SNJ 2511
- Physical State:
- Solid
- Molecular Weight:
- 287.32
- Purity:
- 99%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 446859-33-2
- Immunogen:
- Kinase
- Extra Details:
- RepSox is a potent (IC50 ALK5 auto-P= 4 nM; IC50 TGF-b cellular assay = 23 nM) inhibitor of the TGF-B Beta type I receptor (ALK5).1 RepSox can replace Sox2 in reprogramming adult cells into pluripotent stem cells via induction of Nanog transcription.2 It was able to convert astrocytes into neuronal cells as part of a small molecule cocktail (along with valproic acid and CHIR99021).3,4
- Shipping Conditions:
- Ambient