7alpha-Hydroxycholesterol

Size

£139.00

SKU:: 10-4538
Physical State:: Solid
Molecular Weight:: 402.66
Purity:: 98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 566-26-7
Immunogen:: TLR (Toll-like receptor)
Extra Details:: Metabolite resulting from the action of cholesterol 7 alpha-hydroxylase on cholesterol. 7A Alpha-Hydroxycholesterol is the first intermediate and a rate-limiting step in the major pathway for bile acid synthesis in humans. A pro-inflammatory mediator which upregulates production of CCL2 and MMP9 in macrophages and may promote progression of atherosclerosis.2,3 Possible biomarker for cellular lipid peroxidation.4