GW1100

Size

£153.00

SKU:: 10-4516
Physical State:: Solid
Molecular Weight:: 520.59
Purity:: 96%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 306974-70-9
Immunogen:: GPCR
Extra Details:: Selective antagonist of GPR40. GW1100 inhibits GRP40-mediated Ca2+ increases stimulated GW9508 or linoleic acid (pIC50 = 5.99 for either agonist).1 The effects of GPR40 activation on insulin secretion in cells are also blocked by the addition of GW1100. GW1100 does not influence calcium mobilization mediated by GPR120.