10-4495
TWS119
Size
POA
- SKU:
- 10-4495
- Physical State:
- Solid
- Molecular Weight:
- 318.34
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 601514-19-6
- Immunogen:
- Kinase
- Extra Details:
- TWS-119 is a potent inhibitor of GSK-3B Beta (IC50 = 30 nM).1 At higher concentrations (400 nM), it induces neurogenesis in mouse embryonic stem cells.1 It maintained hepatic stellate cells in the quiescent state.2 TWS119 treatment increased the amount of stem cell-like memory CD8+ T cells3, enhanced metabolic fitness of CD8+ T cells4, and prevented CD8+ differentiation5. It displayed neuroprotective effects in models of cerebral ischemia.6,7 TWS119 greatly increased the efficacy of NK cells against myeloma.8
- Shipping Conditions:
- Ambient