T863

Size

£177.00

SKU:: 10-4460
Physical State:: Solid
Molecular Weight:: 394.48
Purity:: 98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 701232-20-4
Extra Details:: T863 is a potent (IC50 = 49 nM CPM fluorescent assay; 17 nM TLC assay) and selective (against DGAT2 and MGATs 2 and 3) inhibitor of diacylglycerol transferase 1 (DGAT1). In mice, it caused weight loss, increased insulin sensitivity, alleviated hepatic steatosis, and reduced triglyceride and cholesterol levels.