TH257

Size

£158.00

SKU:: 10-4418
Physical State:: White to off-white glassy solid
Molecular Weight:: 422.54
Purity:: >98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 2244678-29-1
Immunogen:: Cytoskeleton|Kinase
Extra Details:: TH257 is a potent (IC50's = 238 nM (LIMK1) and 91 nM (LIMK2)) and highly selective (no off-targets against 468 kinases) allosteric inhibitor of LIM kinase 1/2.1 It inhibited neurite outgrowth in N1E-115 cells in a dose-dependent manner.