10-4408
Cytosporone B
Size
POA
- SKU:
- 10-4408
- Physical State:
- Solid
- Molecular Weight:
- 322.4
- Purity:
- >98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 321661-62-5
- Immunogen:
- Transcription factor
- Extra Details:
- Cytosporone B is a naturally occurring agonist (EC50 = 0.28 nM) of nuclear receptor Nur77.1 It elevated blood glucose levels in fasting mice and induced apoptosis in mouse tumor xenografts. Cytosporone B reduced proinflammatory mediators in various models.2-5 It inhibited esophageal squamous cell carcinoma growth and enhanced anti-PD-1 therapy efficacy.6 Cytosporone B enhanced the anti-tumor activity of natural killer cells against hepatocellular carcinoma.7
- Shipping Conditions:
- Ambient