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10-4403

Bedaquiline

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£149.00

SKU:
10-4403
Additional Names:
R207910|TMC207
Physical State:
Solid
Molecular Weight:
555.50
Purity:
99%
Purification:
HPLC Purified
Storage Conditions:
RT
Supplier:
Focus Biomolecules
CAS Number:
843663-66-1
Immunogen:
Cytochrome/MDR|Protease
Extra Details:
Bedaquiline is a clinically useful antituberculosis agent that is active (MIC's 0.030 to 0.120 ug/mL) against multi-drug resistant strains.1 It interferes with mycobacterial energy metabolism via binding to the oligomeric subunit c (AtpE)2 and subunit 3 of ATP synthase inhibiting ATP production.4 Bedaquiline has recently been found to be an inhibitor (IC50 = 18.7 uM) of the SARS-CoV-2 main protease, 3CLpro.5
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