10-4393
MIF20
Size
£168.00
- SKU:
- 10-4393
- Physical State:
- Solid
- Molecular Weight:
- 238.25
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1191288-81-9
- Extra Details:
- MIF20 is a macrophage inhibitory factor (MIF) agonist (2.5 fold increase in MIF bound to its receptor @ 500 nM).1 It augments MIF-dependent AMPK signaling and limits ischemic cardiac injury. MIF20 protected the heart from ischemia-reperfusion injury via MIF-mediated activation of AMPK.2 It decreased infarct size and preserved systolic function. MIF20 also augments protective metabolic responses by reducing the NADH/NAD ratio leading to a decrease in the accumulation of reactive oxygen species.
- Shipping Conditions:
- Ambient