10-4371
Indacaterol maleate
Size
£139.00
- SKU:
- 10-4371
- Additional Names:
- QAB149
- Physical State:
- Solid
- Molecular Weight:
- 508.57
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 753498-25-8
- Immunogen:
- GPCR|RNA
- Extra Details:
- Indacaterol maleate is a full agonist (pEC50 = 8.06) of the human B Beta2 adrenoceptor.1,2 Clinically important drug for the treatment of chronic obstructive pulmonary disease. Indacaterol blocked colorectal cancer progression in vitro (IC50 = 19.01 uM) and in vivo via inhibition of the splicing factor SRSF6 by binding to its RRM2 domain.3 It also blocked cell migration in metastatic breast cancer MDA-MB-231 cells by a similar mechanism.4
- Shipping Conditions:
- Ambient