10-4294
XMU-MP-1
Size
£177.00
- SKU:
- 10-4294
- Physical State:
- Solid
- Molecular Weight:
- 416.47
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 2061980-01-4
- Immunogen:
- Kinase
- Extra Details:
- XMU-MP-1 is a potent, reversible, and selective inhibitor of the HIPPO pathway kinases MST1 and MST2 (IC50s = 71 nM and 38 nM respectively).1 It promoted liver repair/regeneration in mice and attenuated acetaminophen-induced liver injury. In a subarachnoid hemorrhage mouse model, XMU-MP-1 alleviated neurological deficits, brain edema, neuroinflammation, and white matter injury.2 XMU-MP-1 was also cardioprotective in mice with transverse aortic constriction3 and against ischemia/reperfusion injury4.
- Shipping Conditions:
- Ambient