10-4293
TM-25659
Size
£173.00
- SKU:
- 10-4293
- Physical State:
- Solid
- Molecular Weight:
- 500.61
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 260553-97-7
- Immunogen:
- Transcription factor
- Extra Details:
- TM-25659 is a TAZ activator that significantly increases TAZ nuclear localization. It suppressed PPARG Gamma-dependent adipogenesis and enhanced osteoblast differentiation in vitro and in vivo.1 TM-25659 decreased insulin resistance and inflammation in mice via activation of GCN2 pathways.2 It promoted osteogenic differentiation in both adipose-derived stem cells3 and mesenchymal stem cells4.
- Shipping Conditions:
- Ambient