10-4292
NGI-189
Size
£187.00
- SKU:
- 10-4292
- Physical State:
- Solid
- Molecular Weight:
- 478.63
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 2763063-26-7
- Immunogen:
- Glycosylation
- Extra Details:
- NGI-189 is a second generation (NGI-1) oligosaccharyltransferase (OST) inhibitor (IC50 = 90 nM) with preference for OST-A over OST-B. It prevented N-glycosylation of EGFR mutant NSCLC cells and was tolerated in vivo. NGI-189 prevented tumor growth in YU-006 and YU-101 NSCLC tumor xenograft models.
- Shipping Conditions:
- Ambient