10-4279
RPI-GLYT2-82
Size
£182.00
- SKU:
- 10-4279
- Physical State:
- Solid
- Molecular Weight:
- 443.97
- Purity:
- >98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Immunogen:
- Monoamine receptor
- Extra Details:
- RPI-GLYT2-82 is a reversible, allosteric antagonist (IC50 = 554 nM) of Glycine Transporter 2 (GLYT2) with selectivity over GLYT1. It is also an antagonist of the serotonin receptor 5-HT2A (IC50 = 1.9 uM). RPI-GLYT2-82 displayed efficacy in the CCI and PSNL mouse models of neuropathic pain. It showed no addiction liability and had no on-target side effects.
- Shipping Conditions:
- Ambient