10-4233
CYM-5442
Size
POA
- SKU:
- 10-4233
- Physical State:
- Solid
- Molecular Weight:
- 409.49
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1094042-01-9
- Immunogen:
- GPCR
- Extra Details:
- CYM-5442 is a potent (EC50 = 1.35 nM) and highly selective agonist of sphingosine-1-phosphate receptor 1 (S1P1).1 It binds to a hydrophobic pocket distinct from the orthosteric sphingosine-1-phosphate binding site while still inducing and maintaining lymphopenia. CYM-5442 was active in a mouse model of multiple sclerosis.2
- Shipping Conditions:
- Ambient