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10-4229

L-755,507

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£192.00

SKU:
10-4229
Additional Names:
4-[[(Hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]benzenesulfonamide
Physical State:
Solid
Molecular Weight:
584.73
Purity:
>98%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
159182-43-1
Immunogen:
GPCR
Extra Details:
L-755,507 is a very potent (EC50 = 0.43 nM; IC50 = 13 nM) human B Beta3 adrenergic receptor agonist with >440-fold selectivity of B Beta1/2.1 It elicited lipolysis and metabolic rate elevation in rhesus monkeys.2 L-755,507 has been shown to increase homology-directed repair efficiency by 2- and 3-fold in CRISPR gene editing.3,4
Shipping Conditions:
Ambient