10-4227
RGN6024
Size
£197.00
- SKU:
- 10-4227
- Physical State:
- Solid
- Molecular Weight:
- 403.46
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 3055038-20-2
- Immunogen:
- Cytoskeleton
- Extra Details:
- RGN6024 is an orally bioavailable and brain-penetrant tubulin destabilizer. It inhibits microtubule polymerization by binding to the colchicine binding site of B Beta-tubulin. Active in glioblastoma cell lines with nanomolar potency. RGN6024 was active in vivo in temozolomide-resistant LN-18 and BT142 glioblastoma xenograft models.
- Shipping Conditions:
- Ambient