10-4211
BD1063 dihydrochloride
Size
£149.00
- SKU:
- 10-4211
- Physical State:
- Solid
- Molecular Weight:
- 346.13
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 206996-13-6
- Immunogen:
- ER/Golgi
- Extra Details:
- BD1063 is potent and selective sigma-1 antagonist (IC50's: sigma1 = 9nM, sigma2 = 449nM).1 BD1063 abolished mechanical and thermal hyperalgesia in mice with carrageenan-induced acute inflammation by enhancing the action of endogenous opioid peptides of immune origin in a sigma1 dependent manner.2 BD1063 potentiated u-opioid antinociception in mice in a sigma-dependent manner.3 BD-1063 has been used in animal models to successfully treat compulsive eating4 and excessive ethanol drinking5.
- Shipping Conditions:
- Ambient