10-4200
NE-100
Size
£173.00
- SKU:
- 10-4200
- Physical State:
- Solid
- Molecular Weight:
- 391.97
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 149409-57-4
- Immunogen:
- ER/Golgi
- Extra Details:
- NE-100 is potent inhibitor of the sigma receptor () with selectivity for sigma-1 (IC50 = 1.5 nM) over sigma-2 (IC50 = 85 nM).1,2 NE-100 suppressed ischemia-induced neuronal cell death in mice via upregulation of GPR78 through the ATF6 pathway resulting in suppression of ER stress-induced cell death in a sigma 1 independent manner.3
- Shipping Conditions:
- Ambient