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10-4185

SLC-0111

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£139.00

SKU:
10-4185
Additional Names:
U-104
Physical State:
Solid
Molecular Weight:
309.32
Purity:
>98%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
178606-66-1
Extra Details:
SLC-0111 is a potent inhibitor of carbonic anhydrases IX and XII (Ki = 45 nM IX; 4.5 nM XII)1. Active in multiple cancer models2-5 and has displayed synergism with conventional chemotherapy6. SLC-0111 upregulated CD8+ T cells in murine pancreatic cancer models7 and improved responses to immune checkpoint inhibitors8.
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