10-4170
Gilteritinib
Size
£144.00
- SKU:
- 10-4170
- Additional Names:
- ASP2215
- Physical State:
- Solid
- Molecular Weight:
- 552.72
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1254053-43-4
- Immunogen:
- Kinase
- Extra Details:
- Potent inhibitor of FLT3 (IC50 = 5 nM, wild-type FLT3) with more potent activity against all FLT3 mutants.1 It also potently inhibits Axl (IC50 = 41 nM). Clinically useful in the treatment of acute myeloid leukemia. Gilteritinib has also been shown to inhibit glutamine uptake and utilization via downregulation of glutamine transporters.2
- Shipping Conditions:
- Ambient