10-4145
2E151
Size
£182.00
- SKU:
- 10-4145
- Physical State:
- Solid
- Molecular Weight:
- 497.67
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 2416963-37-4
- Extra Details:
- Vaccine adjuvants are materials that enhance the magnitude and duration of protective immune responses, typically via pattern recognition receptors (PRR). 2E151 is a co-adjuvant that increases the potency of toll-like receptor (TLR) adjuvants and overall enhances T cell stimulation/proliferation and cytokine production.1 It increases intracellular Ca2+ via extracellular Ca2+ influx, leading to NF-kB activation (EC50 = 0.9 uM)2 via IKK/MAPK phosphorylation and NFAT translocation in B cells and monocytes.
- Shipping Conditions:
- Ambient