10-4134
NVS-STG2
Size
£173.00
- SKU:
- 10-4134
- Physical State:
- Solid
- Molecular Weight:
- 427.54
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 3030588-01-0
- Immunogen:
- Molecular glue|STING
- Extra Details:
- NVS-STG2 is a STING agonist that activates human STING by binding in a pocket between the transmembrane domains of neighboring STING dimers in a molecular glue-like manner (AC50 = 5.2 uM). Inactive with mouse STING. NVS-STG2 slowed tumor growth significantly in MC38 tumors inoculated into hSTING knock-in mice.
- Shipping Conditions:
- Ambient