LB244

Size

£197.00

SKU:: 10-4133
Physical State:: Solid
Molecular Weight:: 537.58
Purity:: >98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
Immunogen:: STING
Extra Details:: LB244 is a potent (EC50 = 800 nM THP1 cells) and irreversible STING antagonist with markedly enhanced proteome-wide selectivity compared to parent compound BB-Cl-amidine. Potently inhibits STING signaling in vitro in both mouse and human cells and in vivo when formulated in 20% DMSO.