10-4132
H-151
Size
£163.00
- SKU:
- 10-4132
- Physical State:
- Solid
- Molecular Weight:
- 279.34
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 941987-60-6
- Immunogen:
- STING
- Extra Details:
- H-151 is an inhibitor of the signaling molecule STING in mouse and human cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91. It reduced systemic cytokine response in mice treated with the STING agonist 10-carboxymethyl-9-acridanone and showed efficacy in Trex-/- mice.1 H-151 alleviates microglial dysfunction and a broad spectrum of Alzheimer's disease pathologies in AD mouse models.3
- Shipping Conditions:
- Ambient