C-176

Size

£134.00

SKU:: 10-4130
Physical State:: Solid
Molecular Weight:: 358.09
Purity:: 98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 314054-00-7
Immunogen:: STING
Extra Details:: C-176 is an inhibitor of the signaling molecule STING in mouse cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91. Treatment of Trex-/- mice with C-176 resulted in a significant reduction in serum levels of Type I Interferons and amelioration of systemic inflammation.