10-4119
UNC6934
Size
£153.00
- SKU:
- 10-4119
- Physical State:
- Solid
- Molecular Weight:
- 443.46
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 2561494-77-5
- Immunogen:
- Protein methyltransferase
- Extra Details:
- Potent (IC50 = 104 nM) and selective inhibitor of protein lysine methyltransferase nuclear receptor-binding SET domain-containing 2 (NSD2). It potently binds to the PWWP1 domain antagonizing interaction with nucleosomal H3K36me2. UNC6934 is selective against 14 other human PWWP domains and 33 methyltransferases. Active in a nanoBRET PPI assay in U2OS cells (IC50 = 1.23 uM).
- Shipping Conditions:
- Ambient